This formula was devised by Zhang Jie-bin (a.k.a. Zhang Jing-yue), as with many of Zhang Zhong-jing’s formulas from the Shang Han Lun, this one was so ingeniously designed that its use has been expanded over subsequent centuries to include a broad range of disorders – in this case, those due to Liver Qi constraint with the development of Blood stasis. The Black Pearl variant has additional herbs which may enhance the action of activating the Blood. This formula has a broad range of applications for disorders that may be due to stagnation of the Liver Qi leading to Blood stasis.