Clinical Benefits:

• Liquorice and white peony in combination, in the twice daily dose found in T-Clear, have been shown to stimulate aromatase.^1,2 Aromatase is responsible for converting testosterone to oestrogen.² These powerful herbs also have individual effects. Liquorice blocks the activity of enzymes involved in androgen synthesis and the active components of peony antagonise androgen receptors, resulting in an anti-androgenic effect.^5,6
• Inositol is required for healthy glucose disposal as it is converted to D-chiro-inositol, a second messenger associated with healthy glucose uptake, in healthy people.⁴ Chromium also maintains healthy blood glucose levels by augmenting insulin-dependent GLUT4 membrane translocation thereby aiding the transport of glucose into cells.⁷ Compared to women with normal androgens, women with elevated androgens are more likely to exhibit abdominal adiposity.⁸
• Inositol may support normal testosterone balance.¹ As androgens are a major steroid regulator of human hair growth, inositol may assist women with hormone-mediated hair growth.^1,9 A clinical trial on 46 female subjects with mild to moderate hirsutism showed that when they took 2.0 g inositol plus 200 μg folic acid, twice daily, there was a significant reduction in hirsutism and testosterone (Figure One).¹