Clinical Benefits

• Anti-inflammatory support: Quercetin reduces the risk of free radical induced inflammation and damage via several mechanisms. Grape seed contains constituents that down regulate NF κ-β and MAPκ pathway promoters of inflammation and cyclooxygenase activity.⁴ Milk thistle has been shown to contain anti-inflammatory and antioxidant properties.⁵
• Allergy management: Quercetin may assist in the management of allergies through inhibition of leukotriene synthesis and histamine release.⁶ Quercetin also has strong anti-inflammatory effects and has shown to inhibit LPS induced TNF-α production in macrophages and LPS-induced IL-8 production in lung cells.⁷
• Antioxidant support: Quercetin Protect contains a combination of ingredients to provide antioxidant protection during times of excessive free radical exposure such as inflammation. Constituents found in grape seed provide very effective scavengers of both hydrophilic and lipophilic radicals, shown in vitro.⁸ These include super oxide, hydroxyl, peroxyl and peroxynitrite radicals thus reducing potential oxidative cellular damage.⁴ Vitamin C is an important water-soluble antioxidant that directly scavenges free radical oxygen and nitrogen species.⁹ As an antioxidant, vitamin E has been shown to inhibit reactions involving free radicals by destroying singlet molecular oxygen.²