Clinical Benefits

• The average Australian and New Zealand child can have up to 10 colds per year,^3,4 with 70% of children (2 years of age and over) in day care,⁵ an environment understood to triple the risk of becoming sick.⁶ A randomised, double blind, placebo-controlled trial measured the effect of NCFM^® and Bi-07 on immunity in 326 children aged between three to five years old in day care. There was a significant reduction in the incidence and number of sick days (Figure 1) in children taking NCFM^® and Bi-07. Daily probiotic supplementation also reduced the use of antibiotics as well as days missed from school and day care. The study demonstrated the combination of NCFM^® and Bi-07 worked better than NCFM^® alone.⁷ Known for its immune-modulating actions, LGG^® has also been shown to down regulate the immune system, specifically exerting a modulatory effect via butyrate producing bacteria, in addition to down-regulating regulatory T cells thought to be involved in allergy.^8,9

• Ultra Flora Kids Care is scientifically formulated with extensively researched strains that have been validated results to support gastrointestinal health and bowel function. LGG^® is one of the world's most researched strains, with over 30 studies in children. This strain has a balancing effect in microbial composition, increasing lactobacilli levels and bifidobacteria species, stimulating short chain fatty acid (SCFA) production, while also normalising and restoring the intestinal mucosal barrier.¹⁰ Utilising specific prebiotics (i.e. fructooligosaccharides) and probiotic strains, such as LGG^®, NCFM^® and Bi-07 provides an array of benefits for children. This combination supports prebiotic metabolism, colonic function and regularity, as well as healthy microbiome composition; thereby assisting immune responses including minimising risk of inflammatory issues, pathogenic activity and allergies.^11,12,13
• If children have been taking a course of antibiotics, Ultra Flora Kids Care may assist in restoring healthy flora levels that have been disrupted. Research undertaken in 2015 during the winter period found that 51% of 0 to 4 year olds took at least one antibiotic.¹⁴ LGG^® has been shown to reduce the use of antibiotics for common infections in both infants and children.¹⁵ Further to this, a 2018 Meta-analysis of infants and children who receive probiotics (including LGG^® ) to prevent acute illnesses had a lower risk of being prescribed antibiotics, relative to those who received a placebo.